Base editor treats progeria in mice

Nature

  • RESEARCH SUMMARY

Base editor treats progeria in mice

Access options

doi: https://doi.org/10.1038/d41586-021-01114-8

References

  1. 1.

    Eriksson, M. et al. Nature 423, 293–298 (2003).

    PubMed 
    Article 

    Google Scholar
     

  2. 2.

    De Sandre-Giovannoli, A. et al. Science 300, 2055 (2003).

    PubMed 
    Article 

    Google Scholar
     

  3. 3.

    Gordon, L. B., Brown, W. T. & Collins, F. S. Hutchinson–Gilford Progeria Syndrome (GeneReviews, 2019).


    Google Scholar
     

  4. 4.

    Gordon, L. B. et al. Proc. Natl Acad. Sci. USA 109, 16666–16671 (2012).

    PubMed 
    Article 

    Google Scholar
     

  5. 5.

    Gaudelli, N. M. et al. Nature 551, 464–471 (2017).

    PubMed 
    Article 

    Google Scholar
     

  6. 6.

    Anzalone, A. V., Koblan, L. W. & Liu, D. R. Nature Biotechnol. 38, 824–844 (2020).

    PubMed 
    Article 

    Google Scholar
     

  7. 7.

    Grimm, D. & Zolotukhin, S. Mol. Ther. 23, 1819–1831 (2015).

    PubMed 
    Article 

    Google Scholar
     

Download references

Competing Interests

D.R.L. is a co-founder of Beam Therapeutics, Prime Medicine, Pairwise Plants and Editas Medicine, companies that use genome editing.

Subjects

Nature Briefing

An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday.





Products You May Like

Articles You May Like

‘Summer of indigestion’ will produce big buying opportunities, long-term market bull Tony Dwyer predicts
First Case of Rare Monkeypox Detected in Texas Resident Who Traveled to Nigeria
Ancient star likely created from a colossal hypernova explosion
China launches secretive suborbital vehicle for reusable space transportation system
Influential US climate report moves ahead — under new leadership

Leave a Reply

Your email address will not be published. Required fields are marked *